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Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance.
Colini Baldeschi, Arianna; Zattoni, Marco; Vanni, Silvia; Nikolic, Lea; Ferracin, Chiara; La Sala, Giuseppina; Summa, Maria; Bertorelli, Rosalia; Bertozzi, Sine Mandrup; Giachin, Gabriele; Carloni, Paolo; Bolognesi, Maria Laura; De Vivo, Marco; Legname, Giuseppe.
Affiliation
  • Colini Baldeschi A; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, 34136 Trieste, Italy.
  • Zattoni M; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, 34136 Trieste, Italy.
  • Vanni S; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, 34136 Trieste, Italy.
  • Nikolic L; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, 34136 Trieste, Italy.
  • Ferracin C; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, 34136 Trieste, Italy.
  • La Sala G; Molecular Modeling & Drug Discovery Lab, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Summa M; Translational Pharmacology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Bertorelli R; Translational Pharmacology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Bertozzi SM; Analytical Chemistry Lab, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Giachin G; Department of Chemical Sciences (DiSC), University of Padua, Via F. Marzolo 1, 35131 Padova, Italy.
  • Carloni P; Institute for Advanced Simulations (IAS)-5/Institute for Neuroscience and Medicine (INM)-9, "Computational Medicine", Forschungszentrum Jülich, 52428 Jülich, Germany.
  • Bolognesi ML; Institute for Neuroscience and Medicine (INM)-11, "Molecular Neuroscience and Neuroimaging", Forschungszentrum Jülich, 52428 Jülich, Germany.
  • De Vivo M; Department of Physics, RWTH-Aachen University, 52074 Aachen, Germany.
  • Legname G; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
J Med Chem ; 65(13): 8998-9010, 2022 07 14.
Article in En | MEDLINE | ID: mdl-35771181
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prions / Prion Diseases Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2022 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prions / Prion Diseases Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2022 Document type: Article Affiliation country: Country of publication: