Phylogenetic analysis of torque teno virus in Romania: possible evidence of distinct geographical distribution.
Arch Virol
; 167(11): 2311-2318, 2022 Nov.
Article
in En
| MEDLINE
| ID: mdl-35962263
ABSTRACT
Torque teno virus (TTV) is highly prevalent, but little is known about its circulation in humans. Here, we investigated the geographical distribution and phylogeny of TTV in Romania. A fragment of TTV untranslated region B was sequenced in samples from volunteers across the country. Additional sequences from dialyzed patients were also included in the study. Phylogenetic analysis showed that more than 80% of Romanian sequences clustered with isolates assigned to the species Torque teno virus 1 and Torque teno virus 3 (former genogroup 1), and this analysis discriminated between isolates from the North-East and West regions. Further studies assessing the pathogenic potential of TTV isolates should employ analysis based on genomic regions with phylogenetic resolution below the species level.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Torque teno virus
/
DNA Virus Infections
/
Anelloviridae
Limits:
Humans
Country/Region as subject:
Europa
Language:
En
Journal:
Arch Virol
Year:
2022
Document type:
Article
Affiliation country: