Your browser doesn't support javascript.
loading
One-pot three-component access to 5-hydroxyindoles based on an oxidative dearomatization strategy.
Qiu, Hong; Tong, Lingfeng; Lin, Zhongren; Li, Zheyao; Ren, Haosong; Wang, Teng; Yu, Xinhong.
Affiliation
  • Qiu H; Engineering Research Center of Pharmaceutical Process Chemistry, Ministry of Education, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, and State Key Laboratory of Bioengineering Reactors, East China University of Science & Technology, Shanghai 200237, People's Republic of China.
  • Tong L; Engineering Research Center of Pharmaceutical Process Chemistry, Ministry of Education, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, and State Key Laboratory of Bioengineering Reactors, East China University of Science & Technology, Shanghai 200237, People's Republic of China.
  • Lin Z; Engineering Research Center of Pharmaceutical Process Chemistry, Ministry of Education, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, and State Key Laboratory of Bioengineering Reactors, East China University of Science & Technology, Shanghai 200237, People's Republic of China.
  • Li Z; Engineering Research Center of Pharmaceutical Process Chemistry, Ministry of Education, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, and State Key Laboratory of Bioengineering Reactors, East China University of Science & Technology, Shanghai 200237, People's Republic of China.
  • Ren H; Engineering Research Center of Pharmaceutical Process Chemistry, Ministry of Education, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, and State Key Laboratory of Bioengineering Reactors, East China University of Science & Technology, Shanghai 200237, People's Republic of China.
  • Wang T; College of Chemical Engineering, Beijing Institute of Petrochemical Technology, Beijing 102617, China. wangteng@bipt.edu.cn.
  • Yu X; Engineering Research Center of Pharmaceutical Process Chemistry, Ministry of Education, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, and State Key Laboratory of Bioengineering Reactors, East China University of Science & Technology, Shanghai 200237, People's Republic of China.
Org Biomol Chem ; 20(36): 7241-7244, 2022 09 21.
Article in En | MEDLINE | ID: mdl-36069194
ABSTRACT
A one-pot three-component reaction based on an oxidative dearomatization strategy has been performed to provide facile access to 5-hydroxyindole derivatives through a ZnI2-catalyzed tandem process. The multi-unit reactions for the construction of a new C-C bond and two C-N bonds are simple and efficient under mild conditions, and the yield of the target product is as high as 91%.
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / Indoles Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2022 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / Indoles Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2022 Document type: Article