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Design, Synthesis, and Evaluation of a Set of Carboxylic Acid and Phosphate Prodrugs Derived from HBV Capsid Protein Allosteric Modulator NVR 3-778.
Ji, Xiangkai; Jiang, Xiangyi; Kobayashi, Chisa; Ren, Yujie; Hu, Lide; Gao, Zhen; Kang, Dongwei; Jia, Ruifang; Zhang, Xujie; Zhao, Shujie; Watashi, Koichi; Liu, Xinyong; Zhan, Peng.
Affiliation
  • Ji X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
  • Jiang X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
  • Kobayashi C; Department of Virology II, National Institute of Infectious Diseases, Tokyo 163-8001, Japan.
  • Ren Y; Department of Applied Biological Science, Tokyo University of Science, Noda 278-8510, Japan.
  • Hu L; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
  • Gao Z; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
  • Kang D; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
  • Jia R; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
  • Zhang X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
  • Zhao S; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
  • Watashi K; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
  • Liu X; Department of Virology II, National Institute of Infectious Diseases, Tokyo 163-8001, Japan.
  • Zhan P; Department of Applied Biological Science, Tokyo University of Science, Noda 278-8510, Japan.
Molecules ; 27(18)2022 Sep 14.
Article in En | MEDLINE | ID: mdl-36144715
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / Hepatitis B virus Limits: Animals Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / Hepatitis B virus Limits: Animals Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2022 Document type: Article Affiliation country: Country of publication: