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Cas9 targeted nanopore sequencing with enhanced variant calling improves CYP2D6-CYP2D7 hybrid allele genotyping.
Rubben, Kaat; Tilleman, Laurentijn; Deserranno, Koen; Tytgat, Olivier; Deforce, Dieter; Van Nieuwerburgh, Filip.
Affiliation
  • Rubben K; Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, Belgium.
  • Tilleman L; Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, Belgium.
  • Deserranno K; Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, Belgium.
  • Tytgat O; Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, Belgium.
  • Deforce D; Department of Life Science Technologies, Imec, Leuven, Belgium.
  • Van Nieuwerburgh F; Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, Belgium.
PLoS Genet ; 18(9): e1010176, 2022 09.
Article in En | MEDLINE | ID: mdl-36149915

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 CYP2D6 / Nanopore Sequencing Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2022 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 CYP2D6 / Nanopore Sequencing Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2022 Document type: Article Affiliation country: Country of publication: