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RAS oncogenic activity predicts response to chemotherapy and outcome in lung adenocarcinoma.
East, Philip; Kelly, Gavin P; Biswas, Dhruva; Marani, Michela; Hancock, David C; Creasy, Todd; Sachsenmeier, Kris; Swanton, Charles; Downward, Julian; de Carné Trécesson, Sophie.
Affiliation
  • East P; Bioinformatics and Biostatistics, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Kelly GP; Bioinformatics and Biostatistics, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Biswas D; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Marani M; Oncogene Biology Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Hancock DC; Oncogene Biology Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Creasy T; Oncology Data Science, Oncology Research and Development, AstraZeneca, 200 Orchard Ridge Drive, Gaithersburg, MD, 20878, USA.
  • Sachsenmeier K; Oncology Research and Development, AstraZeneca, 35 Gatehouse Drive, Waltham, MA, 02451, USA.
  • Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Downward J; Oncogene Biology Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK. julian.downward@crick.ac.uk.
  • de Carné Trécesson S; Lung Cancer Group, Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK. julian.downward@crick.ac.uk.
Nat Commun ; 13(1): 5632, 2022 09 26.
Article in En | MEDLINE | ID: mdl-36163168
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenocarcinoma of Lung / Lung Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenocarcinoma of Lung / Lung Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: Country of publication: