Bariatric surgery prevents carotid wall thickness progression.
Wien Klin Wochenschr
; 135(5-6): 151-157, 2023 Mar.
Article
in En
| MEDLINE
| ID: mdl-36205799
ABSTRACT
BACKGROUND:
Bariatric surgery is a treatment option for patients with severe obesity and improves parameters of cardiovascular and/or metabolic disease. Carotid intima media thickness (C-IMT) is a surrogate measure of subclinical atherosclerosis. Previous studies showed short to mid-term arrest and even regression of CIMT progression following bariatric surgery. We aimed to investigate the long-term effect of weight loss on CIMT progression 10 years after bariatric surgery in comparison to a population-based control cohort.METHODS:
In total, 21 eligible patients were examined preoperatively, at 5 and 10 years after bariatric surgery. Anthropometric parameters, plasma triglycerides, total cholesterol, high-density lipoprotein cholesterol (HDL-C), insulin, and glucose were assessed at all three study visits. CIMT was measured via Bmode scans of the common carotid artery. CIMT progression was measured in an age-matched and BMI-matched cohort selected from the population-based Bruneck study to compare with changes in CIMT progression after bariatric surgery.RESULTS:
CIMT remained stable over the 10-year observation period after bariatric surgery. The control cohort showed a significant CIMT progression over 10 years. The difference in CIMT progression over 10 years was significant (pâ¯< 0.01) between both cohorts.CONCLUSION:
Weight loss induced by bariatric surgery halts the natural progression of CIMT over a 10-year observation period.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Carotid Artery Diseases
/
Atherosclerosis
/
Bariatric Surgery
/
Carotid Intima-Media Thickness
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Wien Klin Wochenschr
Year:
2023
Document type:
Article
Affiliation country: