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The Middle East and North Africa Diagnosis and Management Guidelines for Inborn Errors of Immunity.
Baris, Safa; Abolhassani, Hassan; Massaad, Michel J; Al-Nesf, Maryam; Chavoshzadeh, Zahra; Keles, Sevgi; Reisli, Ismail; Tahiat, Azzeddine; Shendi, Hiba Mohammad; Elaziz, Dalia Abd; Belaid, Brahim; Al Dhaheri, Fatima; Haskologlu, Sule; Dogu, Figen; Ben-Mustapha, Imen; Sobh, Ali; Galal, Nermeen; Meshaal, Safa; Elhawary, Rabab; El-Marsafy, Aisha; Alroqi, Fayhan J; Al-Saud, Bandar; Al-Ahmad, Mona; Al Farsi, Tariq; Al Sukaiti, Nashat; Al-Tamemi, Salem; Mehawej, Cybel; Dbaibo, Ghassan; ElGhazali, Gehad; Kilic, Sara Sebnem; Genel, Ferah; Kiykim, Ayca; Musabak, Ugur; Artac, Hasibe; Guner, Sukru Nail; Boukari, Rachida; Djidjik, Reda; Kechout, Nadia; Cagdas, Deniz; El-Sayed, Zeinab Awad; Karakoc-Aydiner, Elif; Alzyoud, Raed; Barbouche, Mohamed Ridha; Adeli, Mehdi; Wakim, Rima Hanna; Reda, Shereen M; Ikinciogullari, Aydan; Ozen, Ahmet; Bousfiha, Aziz; Al-Mousa, Hamoud.
Affiliation
  • Baris S; Faculty of Medicine, Division of Pediatric Allergy and Immunology, Marmara University, Istanbul, Turkey; The Isil Berat Barlan Center for Translational Medicine, Istanbul Jeffrey Modell Foundation Diagnostic Center for Primary Immune Deficiencies, Istanbul, Turkey. Electronic address: safabaris@hotm
  • Abolhassani H; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran; Division of Clinical Immunology, Department of Biosciences and Nutrition, Karolinska Institute, Karolinska University Hospital, Huddinge, Stockholm
  • Massaad MJ; Department of Experimental Pathology, Immunology, and Microbiology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon; Department of Pediatrics and Adolescent Medicine, Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon; Center for Infectious Disease
  • Al-Nesf M; Allergy and Immunology Division, Department of Medicine, Hamad Medical Corporation, Doha, Qatar.
  • Chavoshzadeh Z; Allergy and Clinical Immunology Department, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Keles S; Division of Pediatric Allergy and Immunology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
  • Reisli I; Division of Pediatric Allergy and Immunology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
  • Tahiat A; Laboratory of Immunology, Department of Medical Biology, University of Algiers, Rouiba Hospital, Algiers, Algeria.
  • Shendi HM; Division of Pediatric Allergy and Immunology, Tawam Hospital, Abu Dhabi, United Arab Emirates.
  • Elaziz DA; Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Belaid B; Department of Medical Immunology, Beni Messous University Hospital Center, Faculty of Pharmacy, University of Algiers, Algiers, Algeria.
  • Al Dhaheri F; Department of Pediatrics, Pediatric Infectious Diseases, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
  • Haskologlu S; Department of Pediatric Immunology and Allergy, Ankara University School of Medicine, Ankara, Turkey.
  • Dogu F; Department of Pediatric Immunology and Allergy, Ankara University School of Medicine, Ankara, Turkey.
  • Ben-Mustapha I; Department of Immunology, Institut Pasteur de Tunis and University Tunis El Manar, Tunis, Tunisia.
  • Sobh A; Department of Pediatrics, Mansoura University Children's Hospital, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
  • Galal N; Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Meshaal S; Clinical Pathology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Elhawary R; Clinical Pathology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • El-Marsafy A; Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Alroqi FJ; King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
  • Al-Saud B; Department of Pediatrics, Division of Allergy and Immunology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
  • Al-Ahmad M; Department of Microbiology, College of Medicine, Kuwait University, Kuwait.
  • Al Farsi T; Department of Pediatric Allergy and Clinical Immunology, The Royal Hospital, Muscat, Oman.
  • Al Sukaiti N; Department of Pediatric Allergy and Clinical Immunology, The Royal Hospital, Muscat, Oman.
  • Al-Tamemi S; Department of Child Health, Sultan Qaboos University Hospital, Muscat, Oman.
  • Mehawej C; Department of Human Genetics, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
  • Dbaibo G; Department of Pediatrics and Adolescent Medicine, Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon; Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut,
  • ElGhazali G; Department of Immunology, Sheikh Khalifa Medical City-Union 71-Purehealth, Abu Dhabi, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
  • Kilic SS; Department of Pediatric Immunology and Rheumatology, Faculty of Medicine, Bursa Uludag University, Bursa, Turkey.
  • Genel F; Department of Pediatric Immunology and Allergy, University of Health Sciences Dr. Behcet Uz Children's Hospital, Izmir, Turkey.
  • Kiykim A; Division of Pediatric Allergy and Immunology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Musabak U; Department of Internal Medicine, Division of Immunology and Allergy, Faculty of Medicine, Baskent University, Ankara, Turkey.
  • Artac H; Division of Immunology and Allergy, Department of Pediatrics, Faculty of Medicine, Selcuk University, Konya, Turkey.
  • Guner SN; Division of Pediatric Allergy and Immunology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
  • Boukari R; Department of Pediatrics, Mustapha Pacha Faculty of Medicine, Algiers University, Algeria.
  • Djidjik R; Department of Medical Immunology, Beni Messous University Hospital Center, Faculty of Pharmacy, University of Algiers, Algiers, Algeria.
  • Kechout N; Department of Immunology, Pasteur Institute of Algeria, Faculty of Medicine, Algiers, Algeria.
  • Cagdas D; Department of Pediatrics, Section of Pediatric Immunology, Ihsan Dogramaci Children's Hospital, Institute of Child Health, Hacettepe University Medical School, Ankara, Turkey.
  • El-Sayed ZA; Pediatric Allergy, Immunology and Rheumatology Unit, Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
  • Karakoc-Aydiner E; Faculty of Medicine, Division of Pediatric Allergy and Immunology, Marmara University, Istanbul, Turkey; The Isil Berat Barlan Center for Translational Medicine, Istanbul Jeffrey Modell Foundation Diagnostic Center for Primary Immune Deficiencies, Istanbul, Turkey.
  • Alzyoud R; Section of Immunology, Allergy and Rheumatology, Queen Rania Children Hospital, Amman, Jordan.
  • Barbouche MR; Department of Immunology, Institut Pasteur de Tunis and University Tunis El Manar, Tunis, Tunisia.
  • Adeli M; Department of Immunology, Sidra Medicine, Ar-Rayyan, Qatar.
  • Wakim RH; Department of Pediatrics and Adolescent Medicine, Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon; Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut,
  • Reda SM; Pediatric Allergy, Immunology and Rheumatology Unit, Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
  • Ikinciogullari A; Department of Pediatric Immunology and Allergy, Ankara University School of Medicine, Ankara, Turkey.
  • Ozen A; Faculty of Medicine, Division of Pediatric Allergy and Immunology, Marmara University, Istanbul, Turkey; The Isil Berat Barlan Center for Translational Medicine, Istanbul Jeffrey Modell Foundation Diagnostic Center for Primary Immune Deficiencies, Istanbul, Turkey.
  • Bousfiha A; Laboratory of Clinical Immunology, Inflammation and Allergy, Faculty of Medicine and Pharmacy of Casablanca, Department of pediatric infectious and immunological diseases, Ibn Rushd Children Hospital, King Hassan II University, Casablanca, Morocco.
  • Al-Mousa H; Department of Pediatrics, Division of Allergy and Immunology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
J Allergy Clin Immunol Pract ; 11(1): 158-180.e11, 2023 01.
Article in En | MEDLINE | ID: mdl-36265766
ABSTRACT
Human inborn errors of immunity (IEI) are a group of 485 distinct genetic disorders affecting children and adults. Signs and symptoms of IEI are heterogeneous, and accurate diagnosis can be challenging and depends on the available human expertise and laboratory resources. The Middle East and North Africa (MENA) region has an increased prevalence of IEI because of the high rate of consanguinity with a predominance of autosomal recessive disorders. This area also exhibits more severe disease phenotypes compared with other regions, probably due to the delay in diagnosis. The MENA-IEI registry network has designed protocols and guidelines for the diagnosis and treatment of IEI, taking into consideration the variable regional expertise and resources. These guidelines are primarily meant to improve the care of patients within the region, but can also be followed in other regions with similar patient populations.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Consanguinity Type of study: Diagnostic_studies / Guideline / Risk_factors_studies Limits: Adult / Child / Humans Country/Region as subject: Africa / Asia Language: En Journal: J Allergy Clin Immunol Pract Year: 2023 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Consanguinity Type of study: Diagnostic_studies / Guideline / Risk_factors_studies Limits: Adult / Child / Humans Country/Region as subject: Africa / Asia Language: En Journal: J Allergy Clin Immunol Pract Year: 2023 Document type: Article