Anti-SARS-CoV-2 antibody immunoreactivity profiles during COVID-19 recurrence.
Rev Soc Bras Med Trop
; 55: e01062022, 2022.
Article
in En
| MEDLINE
| ID: mdl-36287469
ABSTRACT
BACKGROUND:
This study aimed to evaluate IgG and IgM levels in COVID-19 recurrence.METHODS:
The serum antibody levels and clinical data from 73 healthcare workers with SARS-CoV-2 divided into seroconverted (n=51) and non-seroconverted (n=22) groups were assessed. The presence of specific anti-nucleocapsid (anti-N) IgM and IgG for SARS-CoV-2 was evaluated. IgG antibodies to the SARS-CoV-2 spike receptor-binding domain were used to confirm non-seroconversion in all negative anti-N.RESULTS:
Four recurrent cases displayed mild symptoms and were non-seroconverted until the recurrence of symptoms.CONCLUSIONS:
Undetectable anti-nucleocapsid IgM and IgG levels may be correlated with symptomatic COVID-19 recurrence.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
COVID-19
Limits:
Humans
Language:
En
Journal:
Rev Soc Bras Med Trop
Year:
2022
Document type:
Article
Affiliation country: