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Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner.
Schumann, Tina; Ramon, Santiago Costas; Schubert, Nadja; Mayo, Mohamad Aref; Hega, Melanie; Maser, Katharina Isabell; Ada, Servi-Remzi; Sydow, Lukas; Hajikazemi, Mona; Badstübner, Markus; Müller, Patrick; Ge, Yan; Shakeri, Farhad; Buness, Andreas; Rupf, Benjamin; Lienenklaus, Stefan; Utess, Barbara; Muhandes, Lina; Haase, Michael; Rupp, Luise; Schmitz, Marc; Gramberg, Thomas; Manel, Nicolas; Hartmann, Gunther; Zillinger, Thomas; Kato, Hiroki; Bauer, Stefan; Gerbaulet, Alexander; Paeschke, Katrin; Roers, Axel; Behrendt, Rayk.
Affiliation
  • Schumann T; Institute for Immunology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Ramon SC; Institute for Immunology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Schubert N; Institute for Immunology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Mayo MA; Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Hega M; Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Maser KI; Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Ada SR; Institute for Immunology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Sydow L; Institute for Immunology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Hajikazemi M; Clinic of Internal Medicine III, Oncology, Hematology, Rheumatology and Clinical Immunology, University Hospital Bonn, Bonn, Germany.
  • Badstübner M; Institute for Immunology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Müller P; Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Ge Y; Institute for Immunology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Shakeri F; Institute for Immunology, University Hospital Heidelberg, Heidelberg, Germany.
  • Buness A; Institute for Medical Biometry, Informatics and Epidemiology, Medical Faculty, University of Bonn, Bonn, Germany.
  • Rupf B; Institute for Genomic Statistics and Bioinformatics, Medical Faculty, University of Bonn, Bonn, Germany.
  • Lienenklaus S; Institute for Medical Biometry, Informatics and Epidemiology, Medical Faculty, University of Bonn, Bonn, Germany.
  • Utess B; Institute for Genomic Statistics and Bioinformatics, Medical Faculty, University of Bonn, Bonn, Germany.
  • Muhandes L; Institute for Immunology, Philipps-University Marburg, Marburg, Germany.
  • Haase M; Institute of Laboratory Animal Science, Hannover Medical School, Hannover, Germany.
  • Rupp L; Institute for Immunology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Schmitz M; Institute for Immunology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Gramberg T; Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Manel N; Department of Pediatric Surgery, University Hospital Dresden, Dresden, Germany.
  • Hartmann G; Institute for Immunology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Zillinger T; Institute for Immunology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Kato H; National Center for Tumor Diseases, Partner Site Dresden, Dresden, Germany.
  • Bauer S; German Cancer Consortium, Partner Site Dresden, and German Cancer Research Center, Heidelberg, Germany.
  • Gerbaulet A; Institute of Clinical and Molecular Virology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
  • Paeschke K; Institut national de la santé et de la recherche médicale U932, Institut Curie, Paris Sciences et Lettres Research University, Paris, France.
  • Roers A; Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Behrendt R; Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
J Exp Med ; 220(1)2023 01 02.
Article in En | MEDLINE | ID: mdl-36346347
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nucleic Acids / Interferon Type I Limits: Animals Language: En Journal: J Exp Med Year: 2023 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nucleic Acids / Interferon Type I Limits: Animals Language: En Journal: J Exp Med Year: 2023 Document type: Article Affiliation country: