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Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors.
Salem, Ibrahim M; Mostafa, Samia M; Salama, Ismail; El-Sabbagh, Osama I; Hegazy, Wael A H; Ibrahim, Tarek S.
Affiliation
  • Salem IM; Medicinal Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt.
  • Mostafa SM; Medicinal Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt.
  • Salama I; Medicinal Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt.
  • El-Sabbagh OI; Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
  • Hegazy WAH; Department of Microbiology and Immunology, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
  • Ibrahim TS; Pharmacy Program, Department of Pharmaceutical Sciences, Oman College of Health Sciences, Muscat, Oman.
J Enzyme Inhib Med Chem ; 38(1): 203-215, 2023 Dec.
Article in En | MEDLINE | ID: mdl-36382444
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Folic Acid Antagonists / Antineoplastic Agents Limits: Female / Humans Language: En Journal: J Enzyme Inhib Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Folic Acid Antagonists / Antineoplastic Agents Limits: Female / Humans Language: En Journal: J Enzyme Inhib Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2023 Document type: Article Affiliation country: Country of publication: