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Discovery of Nanomolar-Affinity Pharmacological Chaperones Stabilizing the Oncogenic p53 Mutant Y220C.
Stephenson Clarke, Joseph R; Douglas, Leon R; Duriez, Patrick J; Balourdas, Dimitrios-Ilias; Joerger, Andreas C; Khadiullina, Raniya; Bulatov, Emil; Baud, Matthias G J.
Affiliation
  • Stephenson Clarke JR; School of Chemistry and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, United Kingdom.
  • Douglas LR; Cancer Research UK, Somers Building, University Hospital Southampton, Tremona Road, Southampton SO16 6YD, United Kingdom.
  • Duriez PJ; Centre for Cancer Immunology, University Hospital Southampton, Coxford Road, Southampton SO16 6YD, United Kingdom.
  • Balourdas DI; Institute of Pharmaceutical Chemistry, Johann Wolfgang Goethe University, Max-von-Laue-Straße 9, 60438 Frankfurt am Main, Germany.
  • Joerger AC; Buchmann Institute for Molecular Life Sciences and Structural Genomics Consortium, Max-von-Laue-Straße 15, 60438 Frankfurt am Main, Germany.
  • Khadiullina R; Institute of Pharmaceutical Chemistry, Johann Wolfgang Goethe University, Max-von-Laue-Straße 9, 60438 Frankfurt am Main, Germany.
  • Bulatov E; Buchmann Institute for Molecular Life Sciences and Structural Genomics Consortium, Max-von-Laue-Straße 15, 60438 Frankfurt am Main, Germany.
  • Baud MGJ; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.
ACS Pharmacol Transl Sci ; 5(11): 1169-1180, 2022 Nov 11.
Article in En | MEDLINE | ID: mdl-36407959
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Pharmacol Transl Sci Year: 2022 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Pharmacol Transl Sci Year: 2022 Document type: Article Affiliation country: