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TLR7 agonist RO7020531 versus placebo in healthy volunteers and patients with chronic hepatitis B virus infection: a randomised, observer-blind, placebo-controlled, phase 1 trial.
Yuen, Man-Fung; Balabanska, Rozalina; Cottreel, Emmanuelle; Chen, Ethan; Duan, Dan; Jiang, Qiudi; Patil, Avinash; Triyatni, Miriam; Upmanyu, Ruchi; Zhu, Yonghong; Canducci, Filippo; Gane, Edward J.
Affiliation
  • Yuen MF; Department of Medicine, Queen Mary Hospital, School of Clinical Medicine and State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong Special Administrative Region, China.
  • Balabanska R; Clinic of Gastroenterology, Acibadem City Clinic Tokuda Hospital, Sofia, Bulgaria.
  • Cottreel E; Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.
  • Chen E; Roche Pharma Product Development China, Shanghai, China.
  • Duan D; Roche Pharma Research and Early Development, Roche Innovation Center, Shanghai, China.
  • Jiang Q; Roche Pharma Research and Early Development, Roche Innovation Center, Shanghai, China.
  • Patil A; Product Development Data Science Department, Roche Products, Welwyn, UK.
  • Triyatni M; Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.
  • Upmanyu R; Product Development Data Science Department, Roche Products, Welwyn, UK.
  • Zhu Y; Roche Pharma Research and Early Development, Roche Innovation Center, Shanghai, China.
  • Canducci F; Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland. Electronic address: filippo.canducci@gmail.com.
  • Gane EJ; Faculty of Medicine, University of Auckland, Auckland, New Zealand.
Lancet Infect Dis ; 23(4): 496-507, 2023 04.
Article in En | MEDLINE | ID: mdl-36509100
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis B, Chronic / Influenza, Human Type of study: Clinical_trials Limits: Humans Country/Region as subject: Europa Language: En Journal: Lancet Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2023 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis B, Chronic / Influenza, Human Type of study: Clinical_trials Limits: Humans Country/Region as subject: Europa Language: En Journal: Lancet Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2023 Document type: Article Affiliation country: