Acute cytomegalovirus hepatitis in an immunocompetent patient: A case report.
World J Clin Cases
; 10(34): 12605-12609, 2022 Dec 06.
Article
in En
| MEDLINE
| ID: mdl-36579114
ABSTRACT
BACKGROUND:
Cytomegalovirus (CMV) infection is usually subclinical and asymptomatic in the healthy population, whereas severe complications occur in immunocompromised patients. CASESUMMARY:
In this case report, we described a rare case of acute CMV hepatitis in a 35-year-old male immunocompetent patient who presented with a history of week-long intermittent fever with nonspecific constitutional symptoms. Acute hepatitis was suspected according to the initial serological tests. After ruling out other etiologies, including viral hepatitis A, B, C, drug, alcohol, autoimmune, and Wilson disease, acute CMV hepatitis was diagnosed based on positive CMV IgM and DNA quantitative tests. Because there was no any local acute hepatitis E reported in Taiwan, so hepatitis E was not checked. The patient recovered both clinically and serologically with symptomatic management and without antiviral therapy within 12 days from the onset of symptom.CONCLUSION:
In conclusion, a diagnosis of CMV infection should be considered when nonspecific prodromal symptoms occur in acute hepatitis with an uncertain etiology. Antiviral therapy should not be used in immunocompetent patient who had no decompensation of the liver, such as this patient. Widely available noninvasive tests for CMV can facilitate early diagnosis if used appropriately. Harm-benefit analysis is essential before using antiviral therapy in immunocompetent patients.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Screening_studies
Language:
En
Journal:
World J Clin Cases
Year:
2022
Document type:
Article
Affiliation country: