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SAR investigation and optimization of benzimidazole-based derivatives as antimicrobial agents against Gram-negative bacteria.
Dokla, Eman M E; Abutaleb, Nader S; Milik, Sandra N; Kandil, Ezzat A E A; Qassem, Omar M; Elgammal, Yehia; Nasr, Maha; McPhillie, Martin J; Abouzid, Khaled A M; Seleem, Mohamed N; Imming, Peter; Adel, Mai.
Affiliation
  • Dokla EME; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt; Institute für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, Halle (Saale), 06120, Germany. Electronic address: emanelawady@pharma.asu.edu.eg.
  • Abutaleb NS; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24061, USA; Department of Microbiology and Immunology, Zagazig University, Zagazig, 44519, Egypt.
  • Milik SN; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt; School of Chemistry, University of Leeds, Leeds, LS2 9JT, United Kingdom.
  • Kandil EAEA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
  • Qassem OM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt; Purdue University Institute of Drug Discovery, Purdue University, West Lafayette, IN, 47907, USA.
  • Elgammal Y; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24061, USA.
  • Nasr M; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
  • McPhillie MJ; School of Chemistry, University of Leeds, Leeds, LS2 9JT, United Kingdom.
  • Abouzid KAM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
  • Seleem MN; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24061, USA; Center for Emerging, Zoonotic and Arthropod-borne Pathogens, Virginia Polytechnic Institute and State University, Bla
  • Imming P; Institute für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, Halle (Saale), 06120, Germany.
  • Adel M; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt. Electronic address: mai.adel@pharma.asu.edu.eg.
Eur J Med Chem ; 247: 115040, 2023 Feb 05.
Article in En | MEDLINE | ID: mdl-36584632
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Escherichia coli / Anti-Infective Agents Limits: Animals / Humans Language: En Journal: Eur J Med Chem Year: 2023 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Escherichia coli / Anti-Infective Agents Limits: Animals / Humans Language: En Journal: Eur J Med Chem Year: 2023 Document type: Article