Tibial quantitative ultrasound compared to dual-energy X-ray absorptiometry in preterm infants.
J Perinatol
; 43(5): 642-646, 2023 05.
Article
in En
| MEDLINE
| ID: mdl-36587053
ABSTRACT
OBJECTIVE:
The gold standard for diagnosing metabolic bone disease in pediatrics is dual-energy x-ray absorptiometry (DXA). Bone quantitative ultrasound (QUS) has increasing applications. This study compared the relationship of DXA to QUS in preterm infants.DESIGN:
Prospective observational study of preterm infants ≤32 weeks gestation or ≤1800 grams at birth. DXA scans measuring bone mineral content (BMC) and tibial QUS scans measuring bone speed of sound (SOS) were obtained near term gestation.RESULTS:
41 infants had bone scans at mean corrected gestation 37.7 ± 2.1 weeks. BMC and SOS showed weak inverse correlation (R2 0.163, p < 0.01). BMC and SOS correlated with parameters at corrected gestational age at the time of the bone scans (p < 0.05-0.001). SOS correlated with birth gestational age (p < 0.001), not BMC.CONCLUSIONS:
A statistically significant weak inverse correlation between DXA and QUS was observed. QUS may have advantages over DXA.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Infant, Premature
/
Bone Density
Type of study:
Observational_studies
Limits:
Child
/
Humans
/
Newborn
Language:
En
Journal:
J Perinatol
Journal subject:
PERINATOLOGIA
Year:
2023
Document type:
Article
Affiliation country: