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microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis.
Ahangari, Farida; Price, Nathan L; Malik, Shipra; Chioccioli, Maurizio; Bärnthaler, Thomas; Adams, Taylor S; Kim, Jooyoung; Pradeep, Sai Pallavi; Ding, Shuizi; Cosmos, Carlos; Rose, Kadi-Ann S; McDonough, John E; Aurelien, Nachelle R; Ibarra, Gabriel; Omote, Norihito; Schupp, Jonas C; DeIuliis, Giuseppe; Villalba Nunez, Julian A; Sharma, Lokesh; Ryu, Changwan; Dela Cruz, Charles S; Liu, Xinran; Prasse, Antje; Rosas, Ivan; Bahal, Raman; Fernández-Hernando, Carlos; Kaminski, Naftali.
Affiliation
  • Ahangari F; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Price NL; Vascular Biology and Therapeutics Program, Yale Center for Molecular and System Metabolism, Department of Comparative Medicine, and Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Malik S; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, Maryland, USA.
  • Chioccioli M; Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut, USA.
  • Bärnthaler T; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Adams TS; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Kim J; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
  • Pradeep SP; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Ding S; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Cosmos C; Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut, USA.
  • Rose KS; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • McDonough JE; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Aurelien NR; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Ibarra G; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Omote N; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Schupp JC; Department of Internal Medicine, Weill Cornell Hospital Medicine, New York, New York, USA.
  • DeIuliis G; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Villalba Nunez JA; Life Span Medical Group, Department of Internal Medicine, Rhode Island Hospital, Providence, Rhode Island, USA.
  • Sharma L; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Ryu C; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Dela Cruz CS; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Liu X; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Prasse A; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Rosas I; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Bahal R; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Fernández-Hernando C; Center for Cellular and Molecular Imaging (CCMI), Department of Cell Biology, Yale School of Medicine, New Haven, Connecticut, USA.
  • Kaminski N; Department of Pneumology, University of Hannover, Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.
JCI Insight ; 8(4)2023 02 22.
Article in En | MEDLINE | ID: mdl-36626225

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / MicroRNAs / Idiopathic Pulmonary Fibrosis / Macrophages Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: JCI Insight Year: 2023 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / MicroRNAs / Idiopathic Pulmonary Fibrosis / Macrophages Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: JCI Insight Year: 2023 Document type: Article Affiliation country: Country of publication: