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Design of nanobody-based bispecific constructs by in silico affinity maturation and umbrella sampling simulations.
Bai, Zixuan; Wang, Jiewen; Li, Jiaqi; Yuan, Haibin; Wang, Ping; Zhang, Miao; Feng, Yuanhang; Cao, Xiangtong; Cao, Xiangan; Kang, Guangbo; de Marco, Ario; Huang, He.
Affiliation
  • Bai Z; Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China.
  • Wang J; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
  • Li J; Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China.
  • Yuan H; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
  • Wang P; Institute of Shaoxing, Tianjin University, Zhejiang 312300, China.
  • Zhang M; Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China.
  • Feng Y; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
  • Cao X; Institute of Shaoxing, Tianjin University, Zhejiang 312300, China.
  • Cao X; Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China.
  • Kang G; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
  • de Marco A; Tianjin Modern Innovative TCM Technology Co. Ltd., Tianjin, China.
  • Huang H; Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China.
Comput Struct Biotechnol J ; 21: 601-613, 2023.
Article in En | MEDLINE | ID: mdl-36659922
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Comput Struct Biotechnol J Year: 2023 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Comput Struct Biotechnol J Year: 2023 Document type: Article Affiliation country: