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Information-Rich, Dual-Function 13C/2H-Isotopic Crosstalk NMR Assay for Human Serine Racemase (hSR) Provides a PLP-Enzyme "Partitioning Fingerprint" and Reveals Disparate Chemotypes for hSR Inhibition.
Ramos de Dios, Stephany M; Hass, Jared L; Graham, Danielle L; Kumar, Nivesh; Antony, Aina E; Morton, Martha D; Berkowitz, David B.
Affiliation
  • Ramos de Dios SM; Department of Chemistry, University of Nebraska, Lincoln, Lincoln, Nebraska 68588, United States.
  • Hass JL; Department of Chemistry, University of Nebraska, Lincoln, Lincoln, Nebraska 68588, United States.
  • Graham DL; Department of Chemistry, University of Nebraska, Lincoln, Lincoln, Nebraska 68588, United States.
  • Kumar N; Department of Chemistry, University of Nebraska, Lincoln, Lincoln, Nebraska 68588, United States.
  • Antony AE; Department of Chemistry, University of Nebraska, Lincoln, Lincoln, Nebraska 68588, United States.
  • Morton MD; Department of Chemistry, University of Nebraska, Lincoln, Lincoln, Nebraska 68588, United States.
  • Berkowitz DB; Department of Chemistry, University of Nebraska, Lincoln, Lincoln, Nebraska 68588, United States.
J Am Chem Soc ; 145(5): 3158-3174, 2023 02 08.
Article in En | MEDLINE | ID: mdl-36696670
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protons / Pyridoxal Phosphate Limits: Humans Language: En Journal: J Am Chem Soc Year: 2023 Document type: Article Affiliation country:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protons / Pyridoxal Phosphate Limits: Humans Language: En Journal: J Am Chem Soc Year: 2023 Document type: Article Affiliation country: