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Catalytic site mutations confer multiple states of G protein activation.
Hewitt, Natalie; Ma, Ning; Arang, Nadia; Martin, Sarah A; Prakash, Ajit; DiBerto, Jeffrey F; Knight, Kevin M; Ghosh, Soumadwip; Olsen, Reid H J; Roth, Bryan L; Gutkind, J Silvio; Vaidehi, Nagarajan; Campbell, Sharon L; Dohlman, Henrik G.
Affiliation
  • Hewitt N; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Ma N; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.
  • Arang N; Department of Pharmacology, University of California, San Diego, San Diego, CA 92093, USA.
  • Martin SA; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.
  • Prakash A; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • DiBerto JF; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Knight KM; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Ghosh S; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Olsen RHJ; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.
  • Roth BL; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Gutkind JS; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Vaidehi N; Department of Pharmacology, University of California, San Diego, San Diego, CA 92093, USA.
  • Campbell SL; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.
  • Dohlman HG; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.
Sci Signal ; 16(772): eabq7842, 2023 02 14.
Article in En | MEDLINE | ID: mdl-36787384
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heterotrimeric GTP-Binding Proteins / Glutamine Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2023 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heterotrimeric GTP-Binding Proteins / Glutamine Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2023 Document type: Article Affiliation country: