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Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner.
Hoeft, Konrad; Schaefer, Gideon J L; Kim, Hyojin; Schumacher, David; Bleckwehl, Tore; Long, Qingqing; Klinkhammer, Barbara Mara; Peisker, Fabian; Koch, Lars; Nagai, James; Halder, Maurice; Ziegler, Susanne; Liehn, Elisa; Kuppe, Christoph; Kranz, Jennifer; Menzel, Sylvia; Costa, Ivan; Wahida, Adam; Boor, Peter; Schneider, Rebekka K; Hayat, Sikander; Kramann, Rafael.
Affiliation
  • Hoeft K; Division of Nephrology and Clinical Immunology, RWTH Aachen University, Aachen, Germany; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
  • Schaefer GJL; Division of Nephrology and Clinical Immunology, RWTH Aachen University, Aachen, Germany; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
  • Kim H; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
  • Schumacher D; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany; Department of Anesthesiology, RWTH Aachen University, Aachen, Germany.
  • Bleckwehl T; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
  • Long Q; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
  • Klinkhammer BM; Department of Pathology, RWTH Aachen University, Aachen, Germany.
  • Peisker F; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
  • Koch L; Division of Nephrology and Clinical Immunology, RWTH Aachen University, Aachen, Germany; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
  • Nagai J; Institute for Computational Genomics, RWTH Aachen University Hospital, Aachen, Germany; Joint Research Center for Computational Biomedicine, RWTH Aachen University Hospital, Aachen, Germany.
  • Halder M; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
  • Ziegler S; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
  • Liehn E; Institute for Molecular Medicine, University of South Denmark, Odense, Denmark.
  • Kuppe C; Division of Nephrology and Clinical Immunology, RWTH Aachen University, Aachen, Germany; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
  • Kranz J; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany; Department of Urology, RWTH Aachen University, Aachen, Germany; Department of Urology and Kidney Transplantation, Martin-Luther-University, Halle (Saale), Germany.
  • Menzel S; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
  • Costa I; Institute for Computational Genomics, RWTH Aachen University Hospital, Aachen, Germany; Joint Research Center for Computational Biomedicine, RWTH Aachen University Hospital, Aachen, Germany.
  • Wahida A; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany; Division of Gynecological Oncology, National Center for Tumor Diseases (NCT), Heidelberg, Germany.
  • Boor P; Division of Nephrology and Clinical Immunology, RWTH Aachen University, Aachen, Germany; Department of Pathology, RWTH Aachen University, Aachen, Germany.
  • Schneider RK; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands; Department of Cell Biology, Institute for Biomedical Technologies, RWTH Aachen University, Aachen, Germany.
  • Hayat S; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
  • Kramann R; Division of Nephrology and Clinical Immunology, RWTH Aachen University, Aachen, Germany; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany; Department of Internal Medicine, Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, the Netherland
Cell Rep ; 42(2): 112131, 2023 02 28.
Article in En | MEDLINE | ID: mdl-36807143
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myofibroblasts / Macrophages Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Rep Year: 2023 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myofibroblasts / Macrophages Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Rep Year: 2023 Document type: Article Affiliation country: