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A photoswitchable inhibitor of TREK channels controls pain in wild-type intact freely moving animals.
Landra-Willm, Arnaud; Karapurkar, Ameya; Duveau, Alexia; Chassot, Anne Amandine; Esnault, Lucille; Callejo, Gerard; Bied, Marion; Häfner, Stephanie; Lesage, Florian; Wdziekonski, Brigitte; Baron, Anne; Fossat, Pascal; Marsollier, Laurent; Gasull, Xavier; Boué-Grabot, Eric; Kienzler, Michael A; Sandoz, Guillaume.
Affiliation
  • Landra-Willm A; Université Côte d'Azur, CNRS, INSERM, iBV, Nice, France.
  • Karapurkar A; Laboratories of Excellence, Ion Channel Science and Therapeutics, Nice, France.
  • Duveau A; Fédération Hospitalo-Universitaire InovPain, Cote d'Azur University, University Hospital Center, Nice, Provence-Alpes-Côte d'Azur, France.
  • Chassot AA; University of Maine Department of Chemistry, 178 Munson Rd., Orono, ME, 04473, USA.
  • Esnault L; Univ. Bordeaux, CNRS, IMN, UMR 5293, F-33000, Bordeaux, France.
  • Callejo G; Université Côte d'Azur, CNRS, INSERM, iBV, Nice, France.
  • Bied M; Laboratories of Excellence, Ion Channel Science and Therapeutics, Nice, France.
  • Häfner S; Fédération Hospitalo-Universitaire InovPain, Cote d'Azur University, University Hospital Center, Nice, Provence-Alpes-Côte d'Azur, France.
  • Lesage F; Univ Angers, Nantes Université, INSERM, Immunology and New Concepts in ImmunoTherapy, INCIT, UMR 1302, Angers, France.
  • Wdziekonski B; Neurophysiology Laboratory, Department of Biomedicine, Medical School, Institute of Neurosciences, Universitat de Barcelona, c. Casanova 143, 08036, Barcelona, Spain.
  • Baron A; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), c. Villarroel 170, 08036, Barcelona, Spain.
  • Fossat P; Université Côte d'Azur, CNRS, INSERM, iBV, Nice, France.
  • Marsollier L; Laboratories of Excellence, Ion Channel Science and Therapeutics, Nice, France.
  • Gasull X; Fédération Hospitalo-Universitaire InovPain, Cote d'Azur University, University Hospital Center, Nice, Provence-Alpes-Côte d'Azur, France.
  • Boué-Grabot E; Université Côte d'Azur, CNRS, INSERM, iBV, Nice, France.
  • Kienzler MA; Laboratories of Excellence, Ion Channel Science and Therapeutics, Nice, France.
  • Sandoz G; Fédération Hospitalo-Universitaire InovPain, Cote d'Azur University, University Hospital Center, Nice, Provence-Alpes-Côte d'Azur, France.
Nat Commun ; 14(1): 1160, 2023 03 01.
Article in En | MEDLINE | ID: mdl-36859433

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Potassium Channels, Tandem Pore Domain Aspects: Ethics Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Potassium Channels, Tandem Pore Domain Aspects: Ethics Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: