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Targeting the deacetylase SIRT6 unveils spliceosome deregulation as exploitable vulnerability for aggressive myeloma.
Gelli, Elisa; Soncini, Debora; Becherini, Pamela; Martinuzzi, Claudia; Todoerti, Katia; Cagnetta, Antonia; Aquino, Sara; Guolo, Fabio; Miglino, Maurizio; Bruzzone, Santina; Nencioni, Alessio; Neri, Antonino; Lemoli, Roberto M; Cea, Michele.
Affiliation
  • Gelli E; Clinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.
  • Soncini D; Clinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.
  • Becherini P; Clinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.
  • Martinuzzi C; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Todoerti K; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Cagnetta A; Department of Hematology, Fondazione Cà Granda IRCCS Policlinico, Milan, Italy.
  • Aquino S; Clinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.
  • Guolo F; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Miglino M; Division of Hematology and Hematopoietic Stem Cell Transplantation Unit, Ospedale Policlinico San Martino, Genoa, Italy.
  • Bruzzone S; Clinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.
  • Nencioni A; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Neri A; Clinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.
  • Lemoli RM; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Cea M; Department of Experimental Medicine, University of Genova, Genova, Italy.
Blood Adv ; 7(14): 3472-3478, 2023 07 25.
Article in En | MEDLINE | ID: mdl-36897214
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sirtuins / Multiple Myeloma Limits: Humans Language: En Journal: Blood Adv Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sirtuins / Multiple Myeloma Limits: Humans Language: En Journal: Blood Adv Year: 2023 Document type: Article Affiliation country: Country of publication: