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Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells.
Park, Sun-Mi; Miyamoto, David K; Han, Grace Y Q; Chan, Mandy; Curnutt, Nicole M; Tran, Nathan L; Velleca, Anthony; Kim, Jun Hyun; Schurer, Alexandra; Chang, Kathryn; Xu, Wenqing; Kharas, Michael G; Woo, Christina M.
Affiliation
  • Park SM; Molecular Pharmacology Program and Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Miyamoto DK; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Han GYQ; Molecular Pharmacology Program and Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chan M; Molecular Pharmacology Program and Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Curnutt NM; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Tran NL; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Velleca A; Molecular Pharmacology Program and Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Kim JH; Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Schurer A; Molecular Pharmacology Program and Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chang K; Molecular Pharmacology Program and Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Xu W; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Kharas MG; Molecular Pharmacology Program and Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: kharasm@mskcc.org.
  • Woo CM; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA; Broad Institute, Cambridge, MA, USA. Electronic address: cwoo@chemistry.harvard.edu.
Cancer Cell ; 41(4): 726-739.e11, 2023 04 10.
Article in En | MEDLINE | ID: mdl-36898380
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Casein Kinase Ialpha Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Casein Kinase Ialpha Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2023 Document type: Article Affiliation country: Country of publication: