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Mechanisms of Cardiac Repair in Cell Therapy.
Collet, Bérénice C; Davis, Darryl R.
Affiliation
  • Collet BC; University of Ottawa Heart Institute, Division of Cardiology, Department of Medicine, University of Ottawa, Ottawa, Canada; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Canada.
  • Davis DR; University of Ottawa Heart Institute, Division of Cardiology, Department of Medicine, University of Ottawa, Ottawa, Canada; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Canada. Electronic address: ddavis@ottawaheart.ca.
Heart Lung Circ ; 32(7): 825-835, 2023 Jul.
Article in En | MEDLINE | ID: mdl-37031061
ABSTRACT
Heart failure is an important cause of morbidity and mortality. More than 20 years ago, special interest was drawn to cell therapy as a means of restoring damaged hearts to working condition. But progress has not been straightforward as many of our initial assumptions turned out to be wrong. In this review, we critically examine the last 20 years of progress in cardiac cell therapy and focus on several of the popular beliefs surrounding cell therapy to illustrate the mechanisms involved in restoring heart function after cardiac injury. Are they true or false?
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell- and Tissue-Based Therapy / Heart Failure Limits: Humans Language: En Journal: Heart Lung Circ Journal subject: ANGIOLOGIA / CARDIOLOGIA Year: 2023 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell- and Tissue-Based Therapy / Heart Failure Limits: Humans Language: En Journal: Heart Lung Circ Journal subject: ANGIOLOGIA / CARDIOLOGIA Year: 2023 Document type: Article Affiliation country: