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Multicomponent Petasis reaction for the identification of pyrazine based multi-target directed anti-Alzheimer's agents: In-silico design, synthesis, and characterization.
Madhav, Hari; Abdel-Rahman, Somaya A; Hashmi, Md Amiruddin; Rahman, Md Ataur; Rehan, Mohammad; Pal, Kavita; Nayeem, Shahid M; Gabr, Moustafa T; Hoda, Nasimul.
Affiliation
  • Madhav H; Drug Design and Synthesis Laboratory, Department of Chemistry, Jamia Millia Islamia, New Delhi, 110025, India.
  • Abdel-Rahman SA; Molecular Imaging Innovations Institute (MI3), Department of Radiology, Weill Cornell Medicine, New York, NY, 10065, USA; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.
  • Hashmi MA; Interdisciplinary Biotechnology Unit, Faculty of Life Sciences, Aligarh Muslim University, Aligarh, 202002, Uttar Pradesh, India.
  • Rahman MA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Rehan M; Max-Planck-Institute für Molekulare Physiologie, Abteilung Chemische Biologie, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.
  • Pal K; Drug Design and Synthesis Laboratory, Department of Chemistry, Jamia Millia Islamia, New Delhi, 110025, India.
  • Nayeem SM; Department of Chemistry, Aligarh Muslim University, Aligarh, 202002, Uttar Pradesh, India.
  • Gabr MT; Molecular Imaging Innovations Institute (MI3), Department of Radiology, Weill Cornell Medicine, New York, NY, 10065, USA. Electronic address: mog4005@med.cornell.edu.
  • Hoda N; Drug Design and Synthesis Laboratory, Department of Chemistry, Jamia Millia Islamia, New Delhi, 110025, India. Electronic address: nhoda@jmi.ac.in.
Eur J Med Chem ; 254: 115354, 2023 Jun 05.
Article in En | MEDLINE | ID: mdl-37043996
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neuroprotective Agents / Alzheimer Disease / Neuroblastoma Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Eur J Med Chem Year: 2023 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neuroprotective Agents / Alzheimer Disease / Neuroblastoma Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Eur J Med Chem Year: 2023 Document type: Article Affiliation country: