High-speed measurement of retinal arterial blood flow in the living human eye with adaptive optics ophthalmoscopy.
Opt Lett
; 48(8): 1994-1997, 2023 Apr 15.
Article
in En
| MEDLINE
| ID: mdl-37058625
ABSTRACT
We present a technique to measure the rapid blood velocity in large retinal vessels with high spatiotemporal resolution. Red blood cell motion traces in the vessels were non-invasively imaged using an adaptive optics near-confocal scanning ophthalmoscope at a frame rate of 200 fps. We developed software to measure blood velocity automatically. We demonstrated the ability to measure the spatiotemporal profiles of the pulsatile blood flow with a maximum velocity of 95-156 mm/s in retinal arterioles with a diameter >100 µm. High-speed and high-resolution imaging increased the dynamic range, enhanced sensitivity, and improved the accuracy when studying retinal hemodynamics.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Retina
/
Retinal Vessels
Limits:
Humans
Language:
En
Journal:
Opt Lett
Year:
2023
Document type:
Article