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Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein.
Shum, Andrew; Zaichick, Sofia; McElroy, Gregory S; D'Alessandro, Karis; Alasady, Milad J; Novakovic, Michaela; Peng, Wesley; Grebenik, Ekaterina A; Chung, Daayun; Flanagan, Margaret E; Smith, Roger; Morales, Alejandro; Stumpf, Laetitia; McGrath, Kaitlyn; Krainc, Dimitri; Mendillo, Marc L; Prakriya, Murali; Chandel, Navdeep S; Caraveo, Gabriela.
Affiliation
  • Shum A; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Zaichick S; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • McElroy GS; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • D'Alessandro K; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Alasady MJ; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Novakovic M; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago IL 60611.
  • Peng W; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Grebenik EA; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Chung D; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Flanagan ME; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago IL 60611.
  • Smith R; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Fienberg School of Medicine, Chicago IL 60611.
  • Morales A; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Stumpf L; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • McGrath K; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Krainc D; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Mendillo ML; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Prakriya M; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Chandel NS; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago IL 60611.
  • Caraveo G; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
Proc Natl Acad Sci U S A ; 120(17): e2217396120, 2023 04 25.
Article in En | MEDLINE | ID: mdl-37068235
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Octopamine / Alpha-Synuclein Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Octopamine / Alpha-Synuclein Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Document type: Article Country of publication: