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Improving the tumor selectivity of T cell engagers by logic-gated dual tumor-targeting.
Shen, Ying; Jin, Shi-Jie; Chen, Yi-Chang; Liu, Wen-Hui; Li, Yi-Ming; Zhao, Wen-Yi; Xu, Ying-Chun; Chen, Shu-Qing; Zhao, Wen-Bin.
Affiliation
  • Shen Y; Institute of Drug Metabolism and Pharmaceutical Analysis & Zhejiang Provincial Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Innovation Institute for Artificial Intelligence in Medicine, Zhejiang University, Hangzhou
  • Jin SJ; Institute of Drug Metabolism and Pharmaceutical Analysis & Zhejiang Provincial Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Chen YC; Institute of Drug Metabolism and Pharmaceutical Analysis & Zhejiang Provincial Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Liu WH; Institute of Drug Metabolism and Pharmaceutical Analysis & Zhejiang Provincial Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Hangzhou Biosun Pharmaceutical Co., Ltd, Hangzhou 310015, China.
  • Li YM; Institute of Drug Metabolism and Pharmaceutical Analysis & Zhejiang Provincial Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Zhao WY; Institute of Drug Metabolism and Pharmaceutical Analysis & Zhejiang Provincial Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Innovation Institute for Artificial Intelligence in Medicine, Zhejiang University, Hangzhou
  • Xu YC; Institute of Drug Metabolism and Pharmaceutical Analysis & Zhejiang Provincial Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Chen SQ; Institute of Drug Metabolism and Pharmaceutical Analysis & Zhejiang Provincial Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. Electronic address: chenshuqing@zju.edu.cn.
  • Zhao WB; Institute of Drug Metabolism and Pharmaceutical Analysis & Zhejiang Provincial Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Innovation Institute for Artificial Intelligence in Medicine, Zhejiang University, Hangzhou
Pharmacol Res ; 192: 106781, 2023 06.
Article in En | MEDLINE | ID: mdl-37119880
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Neoplasms Limits: Animals Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2023 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Neoplasms Limits: Animals Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2023 Document type: Article Country of publication: