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Antithrombin, Protein C, and Protein S: Genome and Transcriptome-Wide Association Studies Identify 7 Novel Loci Regulating Plasma Levels.
Ji, Yuekai; Temprano-Sagrera, Gerard; Holle, Lori A; Bebo, Allison; Brody, Jennifer A; Le, Ngoc-Quynh; Kangro, Kadri; Brown, Michael R; Martinez-Perez, Angel; Sitlani, Colleen M; Suchon, Pierre; Kleber, Marcus E; Emmert, David B; Bilge Ozel, Ayse; Dobson, Dre'Von A; Tang, Weihong; Llobet, Dolors; Tracy, Russell P; Deleuze, Jean-François; Delgado, Graciela E; Gögele, Martin; Wiggins, Kerri L; Souto, Juan Carlos; Pankow, James S; Taylor, Kent D; Trégouët, David-Alexandre; Moissl, Angela P; Fuchsberger, Christian; Rosendaal, Frits R; Morrison, Alanna C; Soria, Jose Manuel; Cushman, Mary; Morange, Pierre-Emmanuel; März, Winfried; Hicks, Andrew A; Desch, Karl C; Johnson, Andrew D; de Vries, Paul S; Wolberg, Alisa S; Smith, Nicholas L; Sabater-Lleal, Maria.
Affiliation
  • Ji Y; Cardiovascular Division, Department of Medicine, University of Minnesota, MN (Y.J.).
  • Temprano-Sagrera G; Unit of genomics of Complex Disease, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, Spain (G.T.-S., N.-Q.L., A.M.-P., J.C.S., J.M.S., M.S.-L.).
  • Holle LA; Department of Pathology and Laboratory Medicine and UNC Blood Research Center, University of North Carolina at Chapel Hill (L.A.H., K.K., D.A.D., A.S.W.).
  • Bebo A; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston (A.B., M.R.B., A.C.M., P.S.d.V.).
  • Brody JA; Department of Medicine, University of Washington (J.A.B., K.L.W.).
  • Le NQ; Unit of genomics of Complex Disease, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, Spain (G.T.-S., N.-Q.L., A.M.-P., J.C.S., J.M.S., M.S.-L.).
  • Kangro K; Department of Pathology and Laboratory Medicine and UNC Blood Research Center, University of North Carolina at Chapel Hill (L.A.H., K.K., D.A.D., A.S.W.).
  • Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston (A.B., M.R.B., A.C.M., P.S.d.V.).
  • Martinez-Perez A; Unit of genomics of Complex Disease, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, Spain (G.T.-S., N.-Q.L., A.M.-P., J.C.S., J.M.S., M.S.-L.).
  • Sitlani CM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle (C.M.S.).
  • Suchon P; C2VN, INSERM, INRAE, Aix Marseille Univ, France (P.S., P.-E.M.).
  • Kleber ME; Laboratory of Haematology, La Timone Hospital, France (P.S., P.-E.M.).
  • Emmert DB; SYNLAB MVZ für Humangenetik Mannheim, Germany (M.E.K.).
  • Bilge Ozel A; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Germany (M.E.K., G.E.D., A.P.M., W.M.).
  • Dobson DA; Institute for Biomedicine (affiliated to the University of Lübeck), Eurac Research, Italy (D.B.E., M.G., C.F., A.A.H.).
  • Tang W; Department of Human Genetics, University of Michigan, C.S. Mott Children's Hospital, Ann Arbor (A.B.O.).
  • Llobet D; Department of Pathology and Laboratory Medicine and UNC Blood Research Center, University of North Carolina at Chapel Hill (L.A.H., K.K., D.A.D., A.S.W.).
  • Tracy RP; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, MN (W.T., J.S.P.).
  • Deleuze JF; Unit of Thrombosis and Hemostasis, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain (D.L., J.C.S.).
  • Delgado GE; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington (R.P.T.).
  • Gögele M; Centre National de Recherche en Génomique Humaine, CEA, France (J.-F.D.).
  • Wiggins KL; Centre d'Etude du Polymorphisme Humain, Fondation Jean Dausset, France (J.-F.D.).
  • Souto JC; Laboratory of Excellence on Medical Genomics (GenMed), France (J.-F.D., D.-A.T.).
  • Pankow JS; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Germany (M.E.K., G.E.D., A.P.M., W.M.).
  • Taylor KD; Institute for Biomedicine (affiliated to the University of Lübeck), Eurac Research, Italy (D.B.E., M.G., C.F., A.A.H.).
  • Trégouët DA; Department of Medicine, University of Washington (J.A.B., K.L.W.).
  • Moissl AP; Unit of genomics of Complex Disease, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, Spain (G.T.-S., N.-Q.L., A.M.-P., J.C.S., J.M.S., M.S.-L.).
  • Fuchsberger C; Unit of Thrombosis and Hemostasis, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain (D.L., J.C.S.).
  • Rosendaal FR; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, MN (W.T., J.S.P.).
  • Morrison AC; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, CA (K.D.T.).
  • Soria JM; Laboratory of Excellence on Medical Genomics (GenMed), France (J.-F.D., D.-A.T.).
  • Cushman M; INSERM UMR 1219, Bordeaux Population Health Research Center, France (D.-A.T.).
  • Morange PE; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Germany (M.E.K., G.E.D., A.P.M., W.M.).
  • März W; Institute of Nutritional Sciences, Friedrich Schiller University Jena, Germany (A.P.M.).
  • Hicks AA; Competence Cluster for Nutrition and Cardiovascular Health(nutriCARD) Halle-Jena-Leipzig, Germany (A.P.M.).
  • Desch KC; Institute for Biomedicine (affiliated to the University of Lübeck), Eurac Research, Italy (D.B.E., M.G., C.F., A.A.H.).
  • Johnson AD; Department of Clinical Epidemiology, Leiden University Medical Center, the Netherlands (F.R.R.).
  • de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston (A.B., M.R.B., A.C.M., P.S.d.V.).
  • Wolberg AS; Larner College of Medicine, University of Vermont, Burlington (M.C.).
  • Smith NL; C2VN, INSERM, INRAE, Aix Marseille Univ, France (P.S., P.-E.M.).
  • Sabater-Lleal M; Laboratory of Haematology, La Timone Hospital, France (P.S., P.-E.M.).
Arterioscler Thromb Vasc Biol ; 43(7): e254-e269, 2023 07.
Article in En | MEDLINE | ID: mdl-37128921
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein C / Protein S Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2023 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein C / Protein S Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2023 Document type: Article Country of publication: