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Circulating tumor DNA reveals mechanisms of lorlatinib resistance in patients with relapsed/refractory ALK-driven neuroblastoma.
Berko, Esther R; Witek, Gabriela M; Matkar, Smita; Petrova, Zaritza O; Wu, Megan A; Smith, Courtney M; Daniels, Alex; Kalna, Joshua; Kennedy, Annie; Gostuski, Ivan; Casey, Colleen; Krytska, Kateryna; Gerelus, Mark; Pavlick, Dean; Ghazarian, Susan; Park, Julie R; Marachelian, Araz; Maris, John M; Goldsmith, Kelly C; Radhakrishnan, Ravi; Lemmon, Mark A; Mossé, Yaël P.
Affiliation
  • Berko ER; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Witek GM; Division of Pediatric Hematology and Oncology, Schneider Children's Medical Center, Petach Tikva, Israel, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Matkar S; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Petrova ZO; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Wu MA; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
  • Smith CM; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Daniels A; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.
  • Kalna J; Yale Cancer Biology Institute, Yale University, West Haven, CT, USA.
  • Kennedy A; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.
  • Gostuski I; Yale Cancer Biology Institute, Yale University, West Haven, CT, USA.
  • Casey C; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.
  • Krytska K; Yale Cancer Biology Institute, Yale University, West Haven, CT, USA.
  • Gerelus M; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Pavlick D; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Ghazarian S; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Park JR; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
  • Marachelian A; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Maris JM; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Goldsmith KC; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Radhakrishnan R; Foundation Medicine, Inc, Cambridge, MA, USA.
  • Lemmon MA; Cancer and Blood Disease Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA.
  • Mossé YP; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Nat Commun ; 14(1): 2601, 2023 05 05.
Article in En | MEDLINE | ID: mdl-37147298
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / Circulating Tumor DNA / Lung Neoplasms / Neuroblastoma Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / Circulating Tumor DNA / Lung Neoplasms / Neuroblastoma Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Country of publication: