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Design, synthesis, and evaluation of antitumor activity of novel C-6 sulfhydryl-substituted and 20-substituted derivatives of celastrol.
Su, Di; Wei, Rong-Yuan; Yan, Zhi-Ming; Zhong, Guo-Hui; Qin, Xiang-Qing; Huang, Shu-Tong; Long, Juan-Yue; Zhang, Feng-Ling; He, Ping; Chen, Zhong-Ji; Yan, Ya-Qian; Jiang, Neng; Tang, Wei-Zhong.
Affiliation
  • Su D; Department of Gastrointestinal Surgery, Guangxi Clinical Research Center for Colorectal Cancer, Guangxi Medical University Cancer Hospital, Nanning, P.R. China.
  • Wei RY; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, P.R. China.
  • Yan ZM; College of Pharmacy, Guangxi Medical University, Nanning, P.R. China.
  • Zhong GH; Department of Pharmacy, Guangxi Medical University Cancer Hospital, Nanning, P.R. China.
  • Qin XQ; Department of Gastrointestinal Surgery, Guangxi Clinical Research Center for Colorectal Cancer, Guangxi Medical University Cancer Hospital, Nanning, P.R. China.
  • Huang ST; Department of Pharmacy, Guangxi Medical University Cancer Hospital, Nanning, P.R. China.
  • Long JY; Department of Pharmacy, Guangxi Medical University Cancer Hospital, Nanning, P.R. China.
  • Zhang FL; College of Pharmacy, Guangxi Medical University, Nanning, P.R. China.
  • He P; College of Pharmacy, Guangxi Medical University, Nanning, P.R. China.
  • Chen ZJ; College of Pharmacy, Guangxi Medical University, Nanning, P.R. China.
  • Yan YQ; College of Pharmacy, Guangxi Medical University, Nanning, P.R. China.
  • Jiang N; Department of Pharmacy, Guangxi Medical University Cancer Hospital, Nanning, P.R. China.
  • Tang WZ; Department of Gastrointestinal Surgery, Guangxi Clinical Research Center for Colorectal Cancer, Guangxi Medical University Cancer Hospital, Nanning, P.R. China.
Chem Biol Drug Des ; 102(2): 316-331, 2023 08.
Article in En | MEDLINE | ID: mdl-37156601
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triterpenes / Antineoplastic Agents Limits: Humans Language: En Journal: Chem Biol Drug Des Journal subject: BIOQUIMICA / FARMACIA / FARMACOLOGIA Year: 2023 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triterpenes / Antineoplastic Agents Limits: Humans Language: En Journal: Chem Biol Drug Des Journal subject: BIOQUIMICA / FARMACIA / FARMACOLOGIA Year: 2023 Document type: Article Country of publication: