Epileptic seizures associated with progressive multifocal leukoencephalopathy in HIV-infected patients in Korea.
J Neurovirol
; 29(3): 325-330, 2023 06.
Article
in En
| MEDLINE
| ID: mdl-37294409
ABSTRACT
We investigated the incidence and risk factors of seizures related to progressive multifocal leukoencephalopathy (PML) in Korean patients infected with HIV. Of the 34 patients, 14 (41.2%) developed epileptic seizures during a median follow-up of 82 months. The median time from PML diagnosis to seizure onset was 44 months, ranging from 0 to 133 months. Patients with PML who developed seizures more commonly had cognitive impairment and multiple or diffuse lesions on brain MRI. These findings highlight the increased seizure risk among HIV-infected patients with PML at any stage of the disease, particularly in cases with extensive involvement.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
HIV Infections
/
Leukoencephalopathy, Progressive Multifocal
/
Epilepsy
Type of study:
Risk_factors_studies
Limits:
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
J Neurovirol
Journal subject:
NEUROLOGIA
/
VIROLOGIA
Year:
2023
Document type:
Article