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Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma.
Peat, Tyler J; Gaikwad, Snehal M; Dubois, Wendy; Gyabaah-Kessie, Nana; Zhang, Shuling; Gorjifard, Sayeh; Phyo, Zaw; Andres, Megan; Hughitt, V Keith; Simpson, R Mark; Miller, Margaret A; Girvin, Andrew T; Taylor, Andrew; Williams, Daniel; D'Antonio, Nelson; Zhang, Yong; Rajagopalan, Adhithi; Flietner, Evan; Wilson, Kelli; Zhang, Xiaohu; Shinn, Paul; Klumpp-Thomas, Carleen; McKnight, Crystal; Itkin, Zina; Chen, Lu; Kazandijian, Dickran; Zhang, Jing; Michalowski, Aleksandra M; Simmons, John K; Keats, Jonathan; Thomas, Craig J; Mock, Beverly A.
Affiliation
  • Peat TJ; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA. Electronic address: tpeat@purdue.edu.
  • Gaikwad SM; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Dubois W; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Gyabaah-Kessie N; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Zhang S; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Gorjifard S; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA; University of Washington, Seattle, WA, USA.
  • Phyo Z; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA; Johns Hopkins University, Baltimore, MD, USA.
  • Andres M; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA; Johns Hopkins University, Baltimore, MD, USA.
  • Hughitt VK; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Simpson RM; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Miller MA; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA.
  • Girvin AT; Palantir Technologies, Palo Alto, CA, USA.
  • Taylor A; Palantir Technologies, Palo Alto, CA, USA.
  • Williams D; Palantir Technologies, Palo Alto, CA, USA.
  • D'Antonio N; Palantir Technologies, Palo Alto, CA, USA.
  • Zhang Y; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA; Office of Oncologic Diseases, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA.
  • Rajagopalan A; McArdle Research Labs, University of Wisconsin, Madison, WI, USA.
  • Flietner E; McArdle Research Labs, University of Wisconsin, Madison, WI, USA.
  • Wilson K; Chemical Genomics Center, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, Bethesda, MD, USA.
  • Zhang X; Chemical Genomics Center, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, Bethesda, MD, USA.
  • Shinn P; Chemical Genomics Center, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, Bethesda, MD, USA.
  • Klumpp-Thomas C; Chemical Genomics Center, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, Bethesda, MD, USA.
  • McKnight C; Chemical Genomics Center, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, Bethesda, MD, USA.
  • Itkin Z; Chemical Genomics Center, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, Bethesda, MD, USA.
  • Chen L; Chemical Genomics Center, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, Bethesda, MD, USA.
  • Kazandijian D; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.
  • Zhang J; McArdle Research Labs, University of Wisconsin, Madison, WI, USA.
  • Michalowski AM; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Simmons JK; Natera, San Carlos, CA, USA.
  • Keats J; Translational Genomics Research Institute, Phoenix, AZ, USA.
  • Thomas CJ; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA; Chemical Genomics Center, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, Bethesda, MD, USA.
  • Mock BA; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. Electronic address: mockb@mail.nih.gov.
Cancer Lett ; 568: 216284, 2023 08 01.
Article in En | MEDLINE | ID: mdl-37356470
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Multiple Myeloma Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Cancer Lett Year: 2023 Document type: Article Country of publication:
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Multiple Myeloma Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Cancer Lett Year: 2023 Document type: Article Country of publication: