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Contribution analysis of metabolic tissues on systemic exposure of an active metabolite after oral administration of verapamil using a stable isotope-labeled compound.
Kataoka, Makoto; Ohshiro, Shota; Minami, Keiko; Hasegawa, Tsubasa; Higashino, Haruki; Takagi, Toshihide; Togashi, Kazutaka; Mutaguchi, Kuninori; Yamashita, Shinji.
Affiliation
  • Kataoka M; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-Cho, Hirakata, Osaka, 573-0101, Japan. Electronic address: makoto@pharm.setsunan.ac.jp.
  • Ohshiro S; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-Cho, Hirakata, Osaka, 573-0101, Japan.
  • Minami K; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-Cho, Hirakata, Osaka, 573-0101, Japan.
  • Hasegawa T; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-Cho, Hirakata, Osaka, 573-0101, Japan.
  • Higashino H; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-Cho, Hirakata, Osaka, 573-0101, Japan.
  • Takagi T; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-Cho, Hirakata, Osaka, 573-0101, Japan.
  • Togashi K; Pharmaceutical Business Division, Sumika Chemical Analysis Service, Ltd., Osaka, 554-0022, Japan.
  • Mutaguchi K; Pharmaceutical Business Division, Sumika Chemical Analysis Service, Ltd., Osaka, 554-0022, Japan.
  • Yamashita S; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-Cho, Hirakata, Osaka, 573-0101, Japan.
Drug Metab Pharmacokinet ; 51: 100514, 2023 Aug.
Article in En | MEDLINE | ID: mdl-37364522
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Verapamil / Isotopes Type of study: Prognostic_studies Limits: Animals Language: En Journal: Drug Metab Pharmacokinet Journal subject: FARMACOLOGIA / METABOLISMO Year: 2023 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Verapamil / Isotopes Type of study: Prognostic_studies Limits: Animals Language: En Journal: Drug Metab Pharmacokinet Journal subject: FARMACOLOGIA / METABOLISMO Year: 2023 Document type: Article Country of publication: