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Type II Cryoglobulinemic Membranoproliferative Glomerulonephritis Caused by Mucosa-associated Lymphoid Tissue Lymphoma.
Sugihara, Ayano; Ureshino, Hiroshi; Yamasaki, Masatora; Fukuda, Makoto; Yoshihara, Maki; Nonaka, Eriko; Miyazaki, Mariko; Fujita, Mai; Ishii, Keitaro; Kamachi, Kazuharu; Sano, Haruhiko; Okamoto, Sho; Itamura, Hidekazu; Yoshimura, Mariko; Katsuya, Hiroo; Ando, Toshihiko; Aoki, Shigehisa; Ubara, Yoshifumi; Kimura, Shinya.
Affiliation
  • Sugihara A; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Ureshino H; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Yamasaki M; Department of Hematology and Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Japan.
  • Fukuda M; Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Yoshihara M; Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Nonaka E; Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Miyazaki M; Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Fujita M; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Ishii K; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Kamachi K; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Sano H; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Okamoto S; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Itamura H; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Yoshimura M; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Katsuya H; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Ando T; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Aoki S; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
  • Ubara Y; Division of Pathology, Department of Pathology and Microbiology, Faculty of Medicine, Saga University, Japan.
  • Kimura S; Nephrology Center, Toranomon Hospital, Japan.
Intern Med ; 62(13): 1983-1988, 2023.
Article in En | MEDLINE | ID: mdl-37394661
ABSTRACT
A 67-year-old man complained of lower limb edema with a purpuric skin rash. Laboratory tests revealed proteinuria, elevated serum creatinine levels, and low serum albumin levels. The patient was also positive for cryoglobulin in serum, immunoglobulin (Ig) M gammopathy, hypocomplementemia, and rheumatoid factor. He was negative for anti-hepatitis C virus antibodies. A pathological analysis of the renal tissue revealed membranoproliferative glomerulonephritis, common histological features of cryoglobulinemic vasculitis (CV), and mucosa-associated lymphoid tissue lymphoma invasion. Although hematologic malignancy is a rare cause of type II CV, these clinical findings suggest that mucosa-associated lymphoid tissue lymphoma (MALT) lymphoma may have been the cause in the present case.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glomerulonephritis, Membranoproliferative / Lymphoma, B-Cell, Marginal Zone / Cryoglobulinemia / Glomerulonephritis Type of study: Diagnostic_studies / Risk_factors_studies Limits: Aged / Humans / Male Language: En Journal: Intern Med Journal subject: MEDICINA INTERNA Year: 2023 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glomerulonephritis, Membranoproliferative / Lymphoma, B-Cell, Marginal Zone / Cryoglobulinemia / Glomerulonephritis Type of study: Diagnostic_studies / Risk_factors_studies Limits: Aged / Humans / Male Language: En Journal: Intern Med Journal subject: MEDICINA INTERNA Year: 2023 Document type: Article Affiliation country: