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Affinity maturation of antibody fragments: A review encompassing the development from random approaches to computational rational optimization.
Li, Jiaqi; Kang, Guangbo; Wang, Jiewen; Yuan, Haibin; Wu, Yili; Meng, Shuxian; Wang, Ping; Zhang, Miao; Wang, Yuli; Feng, Yuanhang; Huang, He; de Marco, Ario.
Affiliation
  • Li J; School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
  • Kang G; School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
  • Wang J; School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
  • Yuan H; School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
  • Wu Y; Zhejiang Provincial Clinical Research Center for Mental Disorders, School of Mental Health and the Affiliated Kangning Hospital, Institute of Aging, Key Laboratory of Alzheimer's Disease of Zhejiang Province, Wenzhou Medical University, Oujiang Laboratory, Wenzhou, Zhejiang 325035, China.
  • Meng S; School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China.
  • Wang P; New Technology R&D Department, Tianjin Modern Innovative TCM Technology Company Limited, Tianjin 300392, China.
  • Zhang M; School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China; China Resources Biopharmaceutical Company Limited, Beijing 100029, China.
  • Wang Y; School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China; Tianjin Pharmaceutical Da Ren Tang Group Corporation Limited, Traditional Chinese Pharmacy Research Institute, Tianjin Key Laboratory of Quality Control in Chinese Medicine, Tianjin 300457, China; State Key Lab
  • Feng Y; School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China.
  • Huang H; School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China. Electronic address: huang@tju.edu.cn.
  • de Marco A; Laboratory for Environmental and Life Sciences, University of Nova Gorica, Nova Gorica, Slovenia. Electronic address: ario.demarco@ung.si.
Int J Biol Macromol ; 247: 125733, 2023 Aug 30.
Article in En | MEDLINE | ID: mdl-37423452
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin Fragments / Antibodies Type of study: Clinical_trials / Prognostic_studies Language: En Journal: Int J Biol Macromol Year: 2023 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin Fragments / Antibodies Type of study: Clinical_trials / Prognostic_studies Language: En Journal: Int J Biol Macromol Year: 2023 Document type: Article Affiliation country: