The Role of Biologic Mesh and Fundoplication in the Surgical Management of Hiatal Hernias: A Multicenter Evaluation.
Dig Surg
; 40(5): 161-166, 2023.
Article
in En
| MEDLINE
| ID: mdl-37494890
ABSTRACT
INTRODUCTION:
Hiatal hernia repair is associated with substantial recurrence of both hiatal hernia and symptoms of gastroesophageal reflux (GER). While small randomized controlled trials demonstrate limited differences in outcomes with use of mesh or fundoplication type, uncertainty remains.METHODS:
A multicenter, retrospective review of patients undergoing surgical treatment of hiatal hernias between 2015 and 2020 was performed. Patients with mesh and with suture-only repair were compared, and partial versus complete fundoplication was compared. Primary outcomes were hernia recurrence and occurrence of postoperative GER symptoms and dysphagia. Multivariable regression was performed to assess the effect of each intervention on clinical outcomes.RESULTS:
A total of 453 patients from four sites were followed for a median (IQR) of 17 (13) months. On multivariate analysis, mesh had no impact on hernia recurrence (odds ratio 0.993, 95% CI 0.53-1.87, p = 0.982), and fundoplication type did not impact recurrence of postoperative GER symptoms (complete odds ratio 0.607, 95% CI 0.33-1.12, p = 0.112) or dysphagia (complete odds ratio 1.17, 95% CI 0.56-2.43, p = 0.677).CONCLUSION:
During hiatal hernia repair, mesh and fundoplication type do not appear to have substantial impact on GER symptoms, dysphagia, or hernia recurrence. This multicenter study provides real-world evidence to support the findings of small RCTs.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biological Products
/
Deglutition Disorders
/
Laparoscopy
/
Hernia, Hiatal
Type of study:
Clinical_trials
Limits:
Humans
Language:
En
Journal:
Dig Surg
Journal subject:
GASTROENTEROLOGIA
Year:
2023
Document type:
Article
Affiliation country: