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NU-1223, a simplified analog of alstonine, with 5-HT2cR agonist-like activity, rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia.
Rajagopal, Lakshmi; Mahjour, Sanaz; Huang, Mei; Ryan, Chelsea A; Elzokaky, Ahmad; Csakai, Adam J; Orr, Meghan J; Scheidt, Karl; Meltzer, Herbert Y.
Affiliation
  • Rajagopal L; Department of Psychiatry and Behavioral Sciences, Northwestern Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Mahjour S; Department of Psychiatry and Behavioral Sciences, Northwestern Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Huang M; Department of Psychiatry and Behavioral Sciences, Northwestern Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Ryan CA; Department of Psychiatry and Behavioral Sciences, Northwestern Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Elzokaky A; Department of Psychiatry and Behavioral Sciences, Northwestern Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Csakai AJ; Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.
  • Orr MJ; Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.
  • Scheidt K; Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA; Department of Pharmacology, Northwestern Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Meltzer HY; Department of Psychiatry and Behavioral Sciences, Northwestern Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address: h-meltzer@northwestern.edu.
Behav Brain Res ; 454: 114614, 2023 10 02.
Article in En | MEDLINE | ID: mdl-37572758
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Antipsychotic Agents Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Behav Brain Res Year: 2023 Document type: Article Affiliation country:
Fulltext
Add to My VHL
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Antipsychotic Agents Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Behav Brain Res Year: 2023 Document type: Article Affiliation country: