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Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti-PD-1 resistance.
Ajith, Ashwin; Mamouni, Kenza; Horuzsko, Daniel D; Musa, Abu; Dzutsev, Amiran K; Fang, Jennifer R; Chadli, Ahmed; Zhu, Xingguo; Lebedyeva, Iryna; Trinchieri, Giorgio; Horuzsko, Anatolij.
Affiliation
  • Ajith A; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
  • Mamouni K; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
  • Horuzsko DD; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
  • Musa A; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
  • Dzutsev AK; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Fang JR; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Chadli A; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
  • Zhu X; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
  • Lebedyeva I; Department of Chemistry and Physics, Augusta University, Augusta, Georgia, USA.
  • Trinchieri G; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Horuzsko A; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
J Clin Invest ; 133(21)2023 11 01.
Article in En | MEDLINE | ID: mdl-37651197
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myeloid-Derived Suppressor Cells / Melanoma Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2023 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myeloid-Derived Suppressor Cells / Melanoma Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2023 Document type: Article Affiliation country: