[Research progress in the diagnosis and management of proliferative verrucous leukoplakia].
Zhonghua Kou Qiang Yi Xue Za Zhi
; 58(10): 1083-1090, 2023 Oct 09.
Article
in Zh
| MEDLINE
| ID: mdl-37818545
ABSTRACT
Proliferative verrucous leukoplakia (PVL) is one of the oral potentially malignant disorders (OPMD) with the highest malignant potential. PVL tends to be easily misdiagnosed owing to the resemblance in clinical manifestations between PVL and other diseases such as oral leukoplakia or oral lichen planus. PVL is considered as a special type of oral leukoplakia by some scholars, which is characterized by its tendency of recurrence and metastasis, along with its high risk of malignant transformation. So far, the accurate clinic diagnosis and management of PVL are still intractable due to the lack of definite histopathological definition, unified diagnostic criteria and effective treatment modalities. This review aims to provide the clinical practitioners with a series of advices on the clinical diagnosis and management of PVL by systematically reviewing the diagnostic logistics, therapeutic strategies, malignant transformation detection based on tremendous relevant data and evidence-based medicine.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Precancerous Conditions
/
Lichen Planus, Oral
/
Carcinoma, Verrucous
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
Zh
Journal:
Zhonghua Kou Qiang Yi Xue Za Zhi
Journal subject:
ODONTOLOGIA
Year:
2023
Document type:
Article