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Evaluation of the non-linearity of NA808 in liver not reflected in plasma using a rat pharmacokinetic study and PBPK modelling.
Yamane, Mizuki; Ozeki, Kazuhisa; Okano, Ken; Kudo, Toshiyuki; Ito, Kiyomi.
Affiliation
  • Yamane M; Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, Japan.
  • Ozeki K; Translational Research Division, Chugai Pharmaceutical Co., Ltd, Tokyo, Japan.
  • Okano K; Translational Research Division, Chugai Pharmaceutical Co., Ltd, Tokyo, Japan.
  • Kudo T; Clinical Development Division, Chugai Pharmaceutical Co., Ltd, Tokyo, Japan.
  • Ito K; Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, Japan.
Xenobiotica ; 53(6-7): 498-506, 2023 Dec.
Article in En | MEDLINE | ID: mdl-37846493
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Citrates / Liver Limits: Animals Language: En Journal: Xenobiotica Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Citrates / Liver Limits: Animals Language: En Journal: Xenobiotica Year: 2023 Document type: Article Affiliation country: Country of publication: