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Clinically relevant mutations in the PhoR sensor kinase of host-adapted Mycobacterium abscessus isolates impact response to acidic pH and virulence.
Belardinelli, Juan M; Arora, Divya; Avanzi, Charlotte; Wheat, William H; Bryant, Josephine M; Spencer, John S; Blundell, Tom L; Parkhill, Julian; Floto, R Andres; Jackson, Mary.
Affiliation
  • Belardinelli JM; Department of Microbiology, Immunology and Pathology, Mycobacteria Research Laboratories, Colorado State University , Fort Collins, Colorado, USA.
  • Arora D; Department of Medicine, Molecular Immunity Unit, University of Cambridge, MRC-Laboratory of Molecular Biology , Cambridge, United Kingdom.
  • Avanzi C; Department of Microbiology, Immunology and Pathology, Mycobacteria Research Laboratories, Colorado State University , Fort Collins, Colorado, USA.
  • Wheat WH; Department of Microbiology, Immunology and Pathology, Mycobacteria Research Laboratories, Colorado State University , Fort Collins, Colorado, USA.
  • Bryant JM; Department of Medicine, Molecular Immunity Unit, University of Cambridge, MRC-Laboratory of Molecular Biology , Cambridge, United Kingdom.
  • Spencer JS; University of Cambridge Centre for AI in Medicine , Cambridge, United Kingdom.
  • Blundell TL; Department of Microbiology, Immunology and Pathology, Mycobacteria Research Laboratories, Colorado State University , Fort Collins, Colorado, USA.
  • Parkhill J; Department of Biochemistry, University of Cambridge , Cambridge, United Kingdom.
  • Floto RA; Wellcome Sanger Institute , Hinxton, United Kingdom.
  • Jackson M; Department of Veterinary Medicine, University of Cambridge , Cambridge, United Kingdom.
Microbiol Spectr ; 11(6): e0158823, 2023 Dec 12.
Article in En | MEDLINE | ID: mdl-37874174
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mycobacterium abscessus / Mycobacterium Infections, Nontuberculous / Mycobacterium tuberculosis Limits: Humans Language: En Journal: Microbiol Spectr Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mycobacterium abscessus / Mycobacterium Infections, Nontuberculous / Mycobacterium tuberculosis Limits: Humans Language: En Journal: Microbiol Spectr Year: 2023 Document type: Article Affiliation country: Country of publication: