Cellular and molecular characteristics of the premetastatic niches.
Animal Model Exp Med
; 6(5): 399-408, 2023 10.
Article
in En
| MEDLINE
| ID: mdl-37902101
ABSTRACT
The premetastatic niches (PMN) formed by primary tumor-derived molecules regulate distant organs and tissues to further favor tumor colonization. Targeted PMN therapy may prevent tumor metastasis in the early stages, which is becoming increasingly important. At present, there is a lack of in-depth understanding of the cellular and molecular characteristics of the PMN. Here, we summarize current research advances on the cellular and molecular characteristics of the PMN. We emphasize that PMN intervention is a potential therapeutic strategy for early prevention of tumor metastasis, which provides a promising basis for future research and clinical application.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Neoplasm Metastasis
/
Neoplasms
Limits:
Humans
Language:
En
Journal:
Animal Model Exp Med
Year:
2023
Document type:
Article
Affiliation country: