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Redox-active endosomes mediate α5ß1 integrin signaling and promote chondrocyte matrix metalloproteinase production in osteoarthritis.
Miao, Michael Z; Su, Qian Peter; Cui, Yang; Bahnson, Edward M; Li, Gang; Wang, Menglin; Yang, Yuchen; Collins, John A; Wu, Di; Gu, Qisheng; Chubinskaya, Susan; Diekman, Brian O; Yamada, Kenneth M; Loeser, Richard F.
Affiliation
  • Miao MZ; Division of Rheumatology, Allergy, and Immunology and the Thurston Arthritis Research Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Su QP; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Cui Y; Curriculum in Oral and Craniofacial Biomedicine, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Bahnson EM; Cell Biology Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.
  • Li G; School of Biomedical Engineering, Faculty of Engineering and Information Technology, University of Technology Sydney, Sydney, NSW 2007, Australia.
  • Wang M; Division of Rheumatology, Allergy, and Immunology and the Thurston Arthritis Research Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Yang Y; Department of Cell Biology and Physiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Collins JA; Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Wu D; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.
  • Gu Q; eScience Institute, University of Washington, Seattle, WA 98195, USA.
  • Chubinskaya S; Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Diekman BO; State Key Laboratory of Biocontrol, School of Ecology, Sun Yat-sen University, Guangzhou 510275, China.
  • Yamada KM; Department of Orthopaedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
  • Loeser RF; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Sci Signal ; 16(809): eadf8299, 2023 10 31.
Article in En | MEDLINE | ID: mdl-37906629

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Cartilage, Articular Limits: Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2023 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Cartilage, Articular Limits: Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2023 Document type: Article Affiliation country: Country of publication: