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Dynamic Activity Model of Movement Disorders: The Fundamental Role of the Hyperdirect Pathway.
Nambu, Atsushi; Chiken, Satomi; Sano, Hiromi; Hatanaka, Nobuhiko; Obeso, José A.
Affiliation
  • Nambu A; Division of System Neurophysiology, National Institute for Physiological Sciences, Okazaki, Japan.
  • Chiken S; Department of Physiological Sciences, SOKENDAI (Graduate University for Advanced Studies), Okazaki, Japan.
  • Sano H; Division of System Neurophysiology, National Institute for Physiological Sciences, Okazaki, Japan.
  • Hatanaka N; Department of Physiological Sciences, SOKENDAI (Graduate University for Advanced Studies), Okazaki, Japan.
  • Obeso JA; Division of System Neurophysiology, National Institute for Physiological Sciences, Okazaki, Japan.
Mov Disord ; 38(12): 2145-2150, 2023 Dec.
Article in En | MEDLINE | ID: mdl-37986211
ABSTRACT
Schematic illustration of cortically induced dynamic activity changes of the output nuclei of the basal ganglia (the internal segment of the globus pallidus, GPi and the substantia nigra pars reticulata, SNr) in the healthy and diseased states. The height of the dam along the time course controls the expression of voluntary movements. Its alterations could cause a variety of movement disorders, such as Parkinson's disease and hyperkinetic disorders. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Movement Disorders Limits: Humans Language: En Journal: Mov Disord Journal subject: NEUROLOGIA Year: 2023 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Movement Disorders Limits: Humans Language: En Journal: Mov Disord Journal subject: NEUROLOGIA Year: 2023 Document type: Article Affiliation country: