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Modular chimeric cytokine receptors with leucine zippers enhance the antitumour activity of CAR T cells via JAK/STAT signalling.
Bell, Matthew; Lange, Shannon; Sejdiu, Besian I; Ibanez, Jorge; Shi, Hao; Sun, Xiang; Meng, Xiaoxi; Nguyen, Phuong; Sutton, Morgan; Wagner, Jessica; Kc, Anil; Langfitt, Deanna; Patil, Sagar L; Tan, Haiyan; Pandey, Ram Vinay; Li, Yuxin; Yuan, Zuo-Fei; Anido, Alejandro Allo; Ho, Mitchell; Sheppard, Heather; Vogel, Peter; Yu, Jiyang; Peng, Junmin; Chi, Hongbo; Babu, M Madan; Krenciute, Giedre; Gottschalk, Stephen.
Affiliation
  • Bell M; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Lange S; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Sejdiu BI; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Ibanez J; Center of Excellence for Data Driven Discovery, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Shi H; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Sun X; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Meng X; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Nguyen P; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Sutton M; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Wagner J; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Kc A; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Langfitt D; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Patil SL; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Tan H; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Pandey RV; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Li Y; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Yuan ZF; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Anido AA; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Ho M; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Sheppard H; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Vogel P; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Yu J; Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Peng J; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Chi H; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Babu MM; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Krenciute G; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Gottschalk S; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN, USA.
Nat Biomed Eng ; 2023 Nov 30.
Article in En | MEDLINE | ID: mdl-38036617
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Nat Biomed Eng Year: 2023 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Nat Biomed Eng Year: 2023 Document type: Article Affiliation country: Country of publication: