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Four Additional Doses of PEG-L-Asparaginase During the Consolidation Phase in the AIEOP-BFM ALL 2009 Protocol Do Not Improve Outcome and Increase Toxicity in High-Risk ALL: Results of a Randomized Study.
Conter, Valentino; Valsecchi, Maria Grazia; Cario, Gunnar; Zimmermann, Martin; Attarbaschi, Andishe; Stary, Jan; Niggli, Felix; Dalla Pozza, Luciano; Elitzur, Sarah; Silvestri, Daniela; Locatelli, Franco; Möricke, Anja; Engstler, Gernot; Smisek, Petr; Bodmer, Nicole; Barbaric, Draga; Izraeli, Shai; Rizzari, Carmelo; Boos, Joachim; Buldini, Barbara; Zucchetti, Massimo; von Stackelberg, Arend; Matteo, Cristina; Lehrnbecher, Thomas; Lanvers-Kaminsky, Claudia; Cazzaniga, Giovanni; Gruhn, Bernd; Biondi, Andrea; Schrappe, Martin.
Affiliation
  • Conter V; Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
  • Valsecchi MG; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
  • Cario G; Biostatistics and Clinical Epidemiology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
  • Zimmermann M; Department of Pediatrics I, Pediatric Hematology/Oncology, ALL-BFM Study Group, Christian Albrechts University Kiel and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Attarbaschi A; Department of Pediatric Hematology/Oncology, Hannover Medical School, Hannover, Germany.
  • Stary J; Department of Pediatric Hematology and Oncology, St Anna Children's Hospital, Medical University of Vienna, Vienna, Austria.
  • Niggli F; St Anna Children's Cancer Research Institute, Vienna, Austria.
  • Dalla Pozza L; Department of Pediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic.
  • Elitzur S; University Children Hospital Zurich, Department of Oncology, Zurich, Switzerland.
  • Silvestri D; The Cancer Centre for Children, The Children's Hospital at Westmead, Sydney, NSW, Australia.
  • Locatelli F; Department of Pediatric Hematology-Oncology, Schneider Children's Medical Center, Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
  • Möricke A; Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
  • Engstler G; Department of Pediatric Hematology and Oncology, IRCCS Ospedale Bambino Gesù, Rome, Catholic University of the Sacred Heart, Rome, Italy.
  • Smisek P; Department of Pediatrics I, Pediatric Hematology/Oncology, ALL-BFM Study Group, Christian Albrechts University Kiel and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Bodmer N; Department of Pediatric Hematology and Oncology, St Anna Children's Hospital, Medical University of Vienna, Vienna, Austria.
  • Barbaric D; Department of Pediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic.
  • Izraeli S; University Children Hospital Zurich, Department of Oncology, Zurich, Switzerland.
  • Rizzari C; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia.
  • Boos J; Department of Pediatric Hematology-Oncology, Schneider Children's Medical Center, Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
  • Buldini B; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
  • Zucchetti M; Pediatrics, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
  • von Stackelberg A; Department of Paediatric Hematology and Oncology, University Hospital Muenster, Muenster, Germany.
  • Matteo C; Pediatric Hematology, Oncology, and Stem Cell Transplant Division, Maternal and Child Health Department, Padua University, Padua, Italy.
  • Lehrnbecher T; Department of Oncology, Laboratory of Cancer Pharmacology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy.
  • Lanvers-Kaminsky C; Department of Pediatric Oncology and Hematology, Charité - Universitätsmedizin Berlin, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germary.
  • Cazzaniga G; Department of Oncology, Laboratory of Cancer Pharmacology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy.
  • Gruhn B; Department of Pediatrics, Division of Hematology and Oncology, Goethe University Frankfurt, Frankfurt am Main, Germany.
  • Biondi A; Department of Paediatric Hematology and Oncology, University Hospital Muenster, Muenster, Germany.
  • Schrappe M; Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
J Clin Oncol ; 42(8): 915-926, 2024 Mar 10.
Article in En | MEDLINE | ID: mdl-38096462

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asparaginase / Precursor Cell Lymphoblastic Leukemia-Lymphoma Limits: Humans / Infant Language: En Journal: J Clin Oncol Year: 2024 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asparaginase / Precursor Cell Lymphoblastic Leukemia-Lymphoma Limits: Humans / Infant Language: En Journal: J Clin Oncol Year: 2024 Document type: Article Affiliation country: