A quality improvement initiative to reduce antibiotic use in transient tachypnea of the newborn.
J Perinatol
; 44(1): 119-124, 2024 01.
Article
in En
| MEDLINE
| ID: mdl-38123798
ABSTRACT
OBJECTIVE:
Evidence suggests that antibiotics are unnecessary in infants with transient tachypnea of the newborn (TTN) that are low-risk for early-onset sepsis. The aim was to reduce ampicillin and gentamicin days of therapy (DOT) in infants with suspected TTN by 10% within 12 months. STUDYDESIGN:
We used the Model for Improvement to test interventions from August 2019 to September 2021 to decrease antibiotic utilization in low-risk infants with TTN. Interventions included the creation of an evidence-based clinical pathway, admission huddles, and prescriber audit and feedback.RESULTS:
We reduced ampicillin and gentamicin use by 26% and 23%, respectively. In 123 infants with suspected TTN, we sequentially decreased starting antibiotics in this group from 71% to 41%, 13% and 0%. There were no cases of missed bacteremia.CONCLUSION:
Creation of a multidisciplinary antimicrobial stewardship QI team and subsequent interventions were successful in safely reducing antibiotic use in infants with TTN.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Transient Tachypnea of the Newborn
/
Anti-Bacterial Agents
Limits:
Humans
/
Infant
/
Newborn
Language:
En
Journal:
J Perinatol
Journal subject:
PERINATOLOGIA
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: