Membrane Dynamics and Cation Handling in Ferroptosis.
Physiology (Bethesda)
; 39(2): 73-87, 2024 Mar 01.
Article
in En
| MEDLINE
| ID: mdl-38193763
ABSTRACT
Ferroptosis, a regulated cell death hallmarked by excessive lipid peroxidation, is implicated in various (patho)physiological contexts. During ferroptosis, lipid peroxidation leads to a diverse change in membrane properties and the dysregulation of ion homeostasis via the cation channels, ultimately resulting in plasma membrane rupture. This review illuminates cellular membrane dynamics and cation handling in ferroptosis regulation.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ferroptosis
Limits:
Humans
Language:
En
Journal:
Physiology (Bethesda)
Journal subject:
FISIOLOGIA
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: